APOE e2 is associated with less atrophy and slower progression in controls, MCI
  
   Lead Investigator:    Jo Barnes
   Institution      :    UCL Institute of Neurology, London
   E-Mail           :    j.barnes@ucl.ac.uk
   Proposal ID      :    479



   Proposal Description:
   The overarching aim is to determine the APOE e2 phenotype. The specific research questions are:   A) What is the pattern of atrophy and cognitive profile of APOE e2 carriers vs. non-carriers in AD, MCI and controls?   B) Do APOE e2 carriers have a specific symptom profile compared with non-carriers in MCI and AD?  C) What is the change in brain volume and cognitive scores of APOE e2 carriers vs. non-carriers in AD, MCI and controls?